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目的研究病毒性肝炎患者血清中可溶性CD 30检测的临床意义。方法选取安徽省芜湖市皖南医学院附属弋矶山医院于2010年2月~2011年2月收治100例病毒性肝炎患者的临床资料,另取50例ALT正常的乙型肝炎病毒(HBV)携带者,将这150例患者作为治疗组对象。同时收集50名健康体检者作为对照组。最后分析各型病毒性肝炎患者血清中CD 30和ALT水平。结果各型病毒性肝炎患者血清中CD 30和丙氨酸氨基转移酶(ALT)水平与对照组比较,差异有统计意义(P<0.05)。结论病毒性肝炎患者血清中可溶性CD30检测的精确性较高,血清CD30水平可以作为肝炎活动性的检测指标。
Objective To study the clinical significance of serum CD30 in patients with viral hepatitis. Methods The clinical data of 100 patients with viral hepatitis were collected from Yijishan Hospital Affiliated to Wannan Medical College in Wuhu City, Anhui Province from February 2010 to February 2011. Fifty ALT normal HBV carriers Those 150 patients were treated as the treatment group. At the same time, 50 healthy people were collected as the control group. Finally, the serum levels of CD30 and ALT in each type of viral hepatitis were analyzed. Results Serum levels of CD30 and alanine aminotransferase (ALT) in patients with various types of viral hepatitis were significantly different from those in the control group (P <0.05). Conclusions The serum CD30 in patients with viral hepatitis has higher accuracy, and the level of serum CD30 can be used as a marker of hepatitis activity.