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毛细胞黏液样星形细胞瘤(pilomyxoid astrocytoma,PMA)是2007年WHO中枢神经系统肿瘤病理学中新提出的一个分类。它是毛细胞星形细胞瘤(pilocytic astrocytoma,PA)的特殊亚型,患者发病年龄更早,视交叉/下丘脑是病变的常见部位。近些年也有成人PMA及特殊部位PMA的报道。组织学见双极梭形细胞围绕血管生长,有黏液样背景,无PA常见的Rosenthal纤维和嗜酸性颗粒小体。与PA相比,患者预后较差,易局部多次复发或经脑脊液转移甚至死亡。PMA复发后可演变呈典型的PA。
Piloma pilomaxoid astrocytoma (pilomaxoid astrocytoma, PMA) 2007 WHO WHO is a new classification of the tumor pathology. It is a specific subtypes of pilocytic astrocytoma (PA), patients at an earlier age, the optic chiasm / hypothalamus is a common site of lesions. In recent years there are also reports of adult PMA and special part PMA. Histology See bipolar spindle cells surrounding blood vessel growth with mucoid-like background, Rosenthal fibers and eosinophilic granulocytes free of PA. Compared with PA, patients with poor prognosis, easy to multiple local recurrence or metastasis by cerebrospinal fluid and even death. After the recurrence of PMA can evolve typical PA.