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阿的平是近年来临床上常用的一种抗疟药物。这种制剂的功效是众所公认的,但因服药后在肠内吸收迅速,而排泄缓慢且呈积蓄作用,故其所引起的毒性反应并非少见,于国内外书籍杂志上都有所记载。一般常见之副作用为胃肠刺激现象,静脉大量注射可致血管扩张、血压下降,并影晌心肌而使心脏发生障碍,其偶致精神病样之发狂而后移行于嗜眠谵妄,甚至深度昏迷者则为阿的平最严重之副作用,多为时1—2周左右而愈。亦有因抑制造血机能,引起再生障碍性贫血者。然应用小量阿的平引起高热、皮疹样过敏反应者实属罕见。我院1955年3月在所有工休人员应用小量阿的平普遍预防流行性感冒605人中,发生此种反应者一人,占0.17%。为了引起
A Ping is clinically used in recent years, an antimalarial drug. The efficacy of this preparation is well-recognized, but its toxicity is not uncommon because it is absorbed rapidly in the intestine after administration and excretes slowly and accumulates. It has been well documented in domestic and foreign books and magazines. Common side effects of gastrointestinal irritation, a large number of intravenous injection can cause vasodilation, blood pressure, and affect the heart and make the heart of the disorder, and its occasional psychotic-like mad and then migrate to sleep apnea, and even deep coma were A flat of the most serious side effects, mostly for about 1-2 weeks and more. Also because of inhibition of hematopoietic function, causing aplastic anemia. However, the application of a small amount of A caused high fever, rash-like allergic reactions are rare. In our hospital in March 1955, a total of 605 workers taking a small dose of Alzheimer’s for prevention of influenza were employed by all workers, accounting for 0.17% of the responders. To cause