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[目的]探讨前列腺癌患者精浆和血清中抑癌因子 H-rev107和T IG3的表达水平及其与前列腺特异性抗原（PSA）的相关性。[方法]ELISA 法检测前列腺癌患者（试验组）和健康男性（对照组）血清及精浆中 H-rev107、TIG3及PSA的表达水平。[结果]试验组血清中 H-rev107、TIG3及 PSA表达均高于对照组（均 P ＜0．05），H-rev107和TIG3分别与PSA在血清中的水平呈正相关。精浆中 H-rev107的表达试验组高于对照组（ P ＜0．05），但其TIG3和PSA表达两组间比较无统计学意义（ P ＞0．05）。[结论]抑癌因子 H-rev107和 TIG3均表达于前列腺癌的血清及精浆中，H-rev107在血清及精浆均有较高的表达，H-rev107和 TIG3分别与PSA在血清中的水平呈正相关。“,”[Objective] To explore the expressions of tumor suppressors H-rev107 and TIG3 in seminal plasma and serum of patients with prostate carcinoma and their correlation with prostate-specific antigen(PSA) .[Methods] ELISA was used to detect the expression levels of H-rev107 ,TIG3 and PSA in serum and seminal plasma of patients with pros-tate carcinoma(experimental group) and healthy men (control group) .[Results] The expression levels of serum H-rev107 ,TIG3 and PSA in experimental group were higher than those in control group (all P<0 .05) .Serum levels of H-rev107 and TIG3 were positively correlated with PSA ,respectively .The expression of H-rev107 in seminal plasma of ex-perimental group was higher than that in control group ( P0 .05) .[Conclusion] Tumor suppressors H-rev107 and TIG3 are ex-pressed in serum and seminal plasma of prostate cancer .H-rev107 and TIG3 in serum are positively correlated with PSA , respectively .