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目的对冷冻消融治疗房室结折返性心动过速(AVNRT)术中快径有效不应期(FPERP)改变的生理现象进行探讨。方法对26例冷冻消融治疗AVNRT患者行术前、有效靶点冷冻消融术中及术后电生理检查,记录FPERP及AH间期的改变。结果 26例AVNRT患者冷冻消融均成功阻断慢径。共35处有效靶点消融术中可见FPERP较术前暂时性延长(386.29±67.65msvs330.29±71.80ms,P<0.05),术后立即恢复(301.14±73.24msvs330.29±71.80ms,P>0.05),同时AH间期术后较术前无改变(83.80±12.24msvs77.77±12.52ms,P>0.2)。结论 AVNRT冷冻消融慢径术中FPERP暂时性延长,停止消融即刻恢复。
OBJECTIVE: To investigate the physiological changes of fasting effective refractory period (FPERP) during cryoablation of atrioventricular nodal reentrant tachycardia (AVNRT). Methods 26 cases of AVNRT patients undergoing cryoablation were treated with preoperative and effective target cryoablation and postoperative electrophysiological examination, and the changes of FPERP and AH interval were recorded. Results All 26 AVNRT patients successfully blocked the slow pathway by cryoablation. A total of 35 effective target ablation techniques showed that FPERP was temporarily prolonged (386.29 ± 67.65 ms vs 330.29 ± 71.80 ms, P <0.05) and recovered immediately after operation (301.14 ± 73.24 ms vs 330.29 ± 71.80 ms, P> 0.05). At the same time, there was no change in AH interval after operation (83.80 ± 12.24ms vs 77.77 ± 12.52ms, P> 0.2). Conclusions FPERP is temporarily prolonged in AVNRT cryoablation and slow recovery.