Cinromide(3-溴-氮-乙基桂皮酰胺)是一种实验性抗癫痫药,具有新的化学结构,其无毒剂量可有力对抗啮齿动物最大电休克发作与戊四氮引起之发作,对患癫痫之猴也有抗癫痫作用,研究表明Cinromide能大量地代谢为氨基代谢物与酸代谢物,其抗癫痫作用可能是氨基代谢物的作用.用Cinromide治癫痫病人,每天1.2-4.8g,当加到标准抗癫痫治疗剂量时,可使发作频率减少约一半,但未弄清发作控制改善中究竟是由于药物的相互作用或安慰剂的效果,还是Cinromide的直接效果,故作此 Cinromide is an experimental antiepileptic drug with a novel chemical structure whose nontoxic dose is effective against the onset of maximal electrical shock and pentylenetetrazole in rodents. Epilepsy monkeys also have anti-epileptic effects, studies have shown that Cinromide can be largely metabolized to amino metabolites and acid metabolites, the antiepileptic effect may be the role of amino metabolites in patients with epilepsy Cinromide treatment, daily 1.2-4.8g, when When added to standard antiepileptic doses, the frequency of seizures can be reduced by about half, but it is unclear whether the seizure control improvement is due to drug-drug interactions or placebo or to the direct effect of Cinromide