目的　评价非小细胞肺癌 (NSCLC)术前支气管动脉灌注化疗 (BAI)近期疗效。方法　经影像学判断手术切除难度较大 ,或不能手术切除的中心型NSCLC患者 2 0例行前瞻性术前BAI。BAI后行手术切除。结果　BAI治疗前后TNM分类改变 5例 ,其中N下降 1例 ,5例均有T改变 ;临床分期下降 2例。PR 8例 ,缓解率为 40 % ,其中鳞癌 6例 ,腺癌 2例 ;NC 12例 ,其中腺癌 1例 ,其余为鳞癌。BAI前后肺不张改善的 9/ 12例 ( 75 % ) ;与周围组织关系密切或受侵改善的 6 / 15例 ( 37 5 % ) ;纵隔淋巴结肿大缩小的 12 / 18例 ( 6 6 6 7% )。结论　BAI作为NSCLC ,尤其是鳞癌的术前辅助治疗 ,具有一定的近期疗效 ,与其它辅助治疗具有同样重要的临床意义 ,是一种特殊的NSCLC新辅助化疗形式。BAI后CT扫描尚不能完全反应残存肿瘤及肿瘤坏死、纤维化等组织学方面的改变 ,具有局限性。CYFRA2 1 1及动态增强MRI是具有临床应用价值的疗效监测方法 Objective To evaluate the short-term efficacy of preoperative bronchial artery infusion chemotherapy (BAI) in non-small cell lung cancer (NSCLC). Methods Twenty 20 patients with central NSCLC who had difficulty in surgical resection or who could not be surgically removed by imaging were prospectively treated with preoperative BAI. BAI surgical resection. Results The changes of TNM classification before and after BAI were found in 5 cases, of which 1 case had a decrease of N, 5 cases had a change of T, and 2 cases had a decline of clinical stage. PR 8 cases, the remission rate was 40%, of which 6 cases of squamous cell carcinoma, adenocarcinoma in 2 cases; NC 12 cases, including 1 case of adenocarcinoma, the rest squamous cell carcinoma. In 9 of 12 patients (75%) with atelectasis improved before and after BAI, 6/15 (37.5%) with close or better involvement of the surrounding tissue and 12 of 18 patients with mediastinal lymphadenopathy (6 6 6 7%). Conclusion As a preoperative adjuvant therapy for NSCLC, especially squamous cell carcinoma, BAI has certain short-term curative effect. It has the same clinical significance as other adjuvant therapy and is a special form of neoadjuvant chemotherapy for NSCLC. Post-BAI CT scan can not fully reflect the remaining tumor and tumor necrosis, fibrosis and other histological changes, has its limitations. CYFRA2 1 1 and dynamic contrast-enhanced MRI is a clinically useful method of monitoring the effects