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目的探讨非典型鳞状上皮细胞(ASCUS)病例的临床处置策略。方法选取2013年无锡市宫颈癌筛查ASCUS、人乳头瘤病毒(HPV)阳性妇女730例,行阴道镜检查,并在阴道镜下对病变部位或可疑部位行宫颈活检。分析病理结果与年龄及HPV亚型的关系。结果 730例中,炎症577例(79.04%);低度上皮内瘤变(CIN1)及以上153例(20.96%),其中宫颈癌7例。50-54岁年龄段重度病例检出率最高,HPV 16型感染中病理学结果最严重。结论临床处置ASCUS病例,优先考虑查HPV16型,50-54岁年龄段阳性病例行阴道镜检查并行宫颈活检,阴性病例观察随访。
Objective To investigate the clinical treatment strategies of atypical squamous cell (ASCUS) cases. Methods A total of 730 women with cervical cancer screening ASCUS and human papillomavirus (HPV) were screened by colposcopy in 2013 in Wuxi City. Colposcopic biopsy was performed under colposcopy on the diseased or suspicious sites. The relationship between pathological findings and age and HPV subtypes was analyzed. Results Among the 730 cases, 577 cases (79.04%) were inflammation, 153 cases (20.96%) had low grade intraepithelial neoplasia (CIN1) and more than 7 cases were cervical cancer. The highest detection rate of severe cases was found in the 50-54 age group, and the pathological results were most serious in the HPV type 16 infection. Conclusions ASCUS cases were treated clinically, HPV16 was the first priority, and colposcopy and cervical biopsy were performed in 50-54-year-old patients. Negative cases were followed up.