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目的:观察益气健脾方内服熏洗对消化道肿瘤化疗相关性乏力及免疫功能影响。方法:选取我科消化道肿瘤化疗的患者共60例,同一患者随机配对先后接受两次不同方案治疗,对照组单纯化疗,治疗组化疗同时中药益气健脾方内服加熏洗。结果:治疗组疲乏发生率明显低于对照组,饮食量减少明显低于对照组(P<0.05),并且消化道反应治疗组明显低于对照组(P<0.05),治疗后免疫功能明显高于对照组(P<0.05)。结论:益气健脾方内服熏洗能有效减少消化道肿瘤化疗相关性乏力发生,降低化疗副反应,提高免疫功能,提高生活质量,值得临床推广。
OBJECTIVE: To observe the effects of oral administration of Yiqi Jianpi Recipe on chemotherapy-related fatigue and immune function in gastrointestinal cancer. Methods: A total of 60 patients with gastrointestinal cancer chemotherapy in our department were enrolled. One patient was randomized and matched with two different schedules in succession. In the control group, chemotherapy alone and chemotherapy combined with traditional Chinese medicine Qi-invigorating and invigorating the spleen were used for oral administration and fumigation. Results: The incidence of fatigue in the treatment group was significantly lower than that in the control group, and the decrease of dietary intake was significantly lower than that of the control group (P <0.05). The digestive tract response treatment group was significantly lower than that of the control group (P <0.05) In the control group (P <0.05). Conclusion: Oral administration of Yiqi Jianpi Recipe can effectively reduce the incidence of chemotherapy-related fatigue in gastrointestinal cancer, reduce the side effects of chemotherapy, improve the immune function and improve the quality of life, which deserves clinical promotion.