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女性性功能障碍(female sexual dysfunction,FSD)是指女性个体不能参与她所期望的性行为,在性行为过程中不能或难以得到满足,并造成人际关系紧张,是一种与年龄相关的、渐进性发展的严重影响女性生活的常见和多发疾病。绝经期女性由于心理、身体、药物及激素水平改变的影响,绝经后女性比绝经前女性有着更多性功能障碍,目前对于雄激素与FSD之间的关系已受到越来越多的重视。现有证据表明女性中雄激素的缺乏可以导致FSD,而且性欲的降低是它的主要表现。并且最近的研究结果表明雄激素补充治疗不仅可以改善性功能障碍,还能改善情绪、血管舒缩症状。绝经期女性比非绝经期女性更容易发生雄激素缺乏,所以绝经期女性雄激素的使用受到了重视。目前雄激素的治疗方式很多,且雄激素使用的副作用也需要进一步的研究。
Female sexual dysfunction (FSD) refers to the fact that a female individual can not participate in her desired sexual behavior and can not or can not be satisfied during the course of her sexual intercourse and cause interpersonal tension. It is an age-related and gradual Sexual development is a common and frequent disease that affects women’s lives. Postmenopausal women have more sexual dysfunction than premenopausal women due to psychological, physical, pharmacological and hormonal changes. At present, the relationship between androgens and FSD has received more and more attention. Available evidence suggests that lack of androgen in women can lead to FSD, and sexual desire is its main manifestation. And recent results show that androgen replacement therapy can not only improve sexual dysfunction, but also improve mood, vasomotor symptoms. Menopausal women are more likely to develop androgen deficiency than non-menopausal women, so the use of androgens in menopausal women is valued. The current treatment of androgen many ways, and the side effects of androgen use also needs further study.