作者报告15例以顽固性咳嗽为唯一主诉的患儿。(男7,女8例),年龄3～14岁,主要症状为顽固性干咳或刺激性咳嗽,持续3～13个月不等。不论在休息或运动时,均不伴有呼吸困难和喘鸣,有4例患儿用力时咳嗽加重。个人和家庭全部有特应性病史;血液嗜酸性细胞除1例(240/mm~3)外,余均超过正常(360～1350/mm~3),这些提示患儿伴有过敏性素质。胸部X线检查8例示肺过度充气,7例正常。对9例能合作的小儿进行了肺功能测定,均示有支气管痉挛。再结合个人和家族的特应性病史、嗜酸性细胞增多以及用茶碱、舒喘灵治疗有效,提示这种顽固性咳嗽是哮喘的一种表现。本综合征机制不明。作者 The authors report 15 children with refractory cough as the sole complaint. (Male 7, female 8), aged 3 to 14 years old, the main symptoms are intractable dry cough or irritating cough, lasting 3 to 13 months. No breathing difficulties or wheezing were found during rest or exercise, and 4 children had an increased cough when forced. All individuals and families had atopic history; all the blood eosinophils were more than normal (360 ~ 1350 / mm ~ 3) except one case (240 / mm ~ 3). All these suggested that children with allergic quality. Chest X-ray examination 8 cases of lung hyperinflation, 7 cases of normal. Spirometry was performed on 9 children who were able to cooperate, all showing bronchospasm. Combined with personal and family history of atopic diseases, eosinophilia and treatment with theophylline and salbutamol effective, suggesting that this intractable cough is a manifestation of asthma. The mechanism of this syndrome is unknown. Author