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骨髓增生异常综合征(MDS)常见的转归为急性白血病,各家报道不一,介于20-60%。本文报道1例原始细胞过多性难治性贫血(RAEB)的患者经历27个月的难治性血细胞减少后发展为慢粒白血病(CML)。患者,70岁,农民,因贫血疲乏及不适两个月,于1981年3月28日入院。既往史无特殊,体检除苍白外并无其它异常。实验室检查:红细胞比积24%,血红蛋白8.6g/dl,白细胞总数4.2×10~9/l,血小板160×10~9/l。光镜下所见形态学异常有巨红细胞血症、中
Myelodysplastic syndrome (MDS) common outcome of acute leukemia, various reports vary between 20-60%. Here, we report that one patient with primitive refractory anemia (RAEB) developed refractory cytopenia and developed CML after 27 months of refractory cytopenia. The patient, 70 years old, farmer, was hospitalized on March 28, 1981, due to fatigue and discomfort caused by anemia. No previous history, physical examination except pale and no other abnormalities. Laboratory tests: hematocrit 24%, hemoglobin 8.6g / dl, the total number of white blood cells 4.2 × 10 ~ 9 / l, platelets 160 × 10 ~ 9 / l. Morphological abnormalities seen under light microscope, macrocytosis, in