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目的研究婴幼儿轮状病毒肠炎与肝脏损害的关系。方法对106例腹泻患儿用金标法检测大便轮状病毒抗原,检测其肝功能,按照大便轮状病毒抗原检测结果分为观察组(大便轮状病毒抗原阳性组)和对照组(大便轮状病毒抗原阴性组),对其结果进行对比分析。结果观察组与对照组肝功能异常发生率比较差异有统计学意义(P<0.01);肝功能异常发生率与患儿发病年龄比较差异有统计学意义(P<0.01);丙氨酸氨基转移酶升高与临床脱水程度比较差异无统计学意义(P>0.05)。结论婴幼儿轮状病毒肠炎常合并肝脏损害,所致的肝脏损害程度与患儿脱水的严重程度无明显相关性,年龄越小肝功能异常发生率越高。
Objective To study the relationship between infantile rotavirus enteritis and liver damage. Methods 106 children with diarrhea were tested for stool rotavirus antigen by gold standard method and their liver function was tested. According to the results of stool rotavirus antigen test, they were divided into observation group (stool rotavirus positive group) and control group (stool Like virus antigen negative group), the results of comparative analysis. Results There was significant difference in the incidence of liver dysfunction between the observation group and the control group (P <0.01). The incidence of liver dysfunction was significantly different from the onset age of children (P <0.01) There was no significant difference in the degree of enzyme and clinical dehydration (P> 0.05). Conclusion Infantile rotavirus enteritis often associated with liver damage, the degree of liver damage caused by dehydration has no significant correlation with the severity of children with age, the higher the incidence of abnormal liver function.