论文部分内容阅读
复方丹参膏(膏滋)是治疗冠心病、高血压的常用药物之一,收载于《山东省药品标准》一九八六年版, 由丹参、丹皮组成,原标准中只收载了煎膏剂常规检查项目,对内在质量缺乏科学的分析和必要的控制标准。丹参是制剂中的主要组成药物,制剂工艺规定用水煎液。丹参水溶性成分原儿茶醛(protocatechuicaldehyde)为抗心绞痛有效成分。为完善提高该制剂的质量标准,本文以复方丹参膏中原儿茶醛为指标,采用薄层层析——紫外分光光度法进行了含量测定,结果满意,介绍如下。
Compound Salvia miltiorrhiza ointment is one of the commonly used drugs for the treatment of coronary heart disease and hypertension. It is contained in the “Shandong Provincial Drug Standards” 1986 edition. It is composed of Salvia miltiorrhiza and Danpi. The original standard only contained fried ones. Ointment routine inspection items lack scientific analysis and necessary control standards for internal quality. Salvia miltiorrhiza is the main ingredient in the preparation, and the formulation process provides for decoction. The protocatechuicaldehyde, a water-soluble component of Salvia miltiorrhiza, is an effective component of anti-angina pectoris. In order to improve the quality standard of this preparation, the content of protocatechuic aldehyde in compound Danshen extract was determined by thin layer chromatography-ultraviolet spectrophotometry. The results were satisfactory and are described as follows.