论文部分内容阅读
目的:了解荧光素致过敏性休克的特点与危险因素,为临床合理使用荧光素提供参考。方法:检索有关医药数据库有关荧光素致过敏性休克的病例报告,对获得的文献进行统计与分析。结果:共检索到荧光素致过敏性休克病例报告46篇53例。荧光素致过敏性休克的特点:中老年人多见,男女比例为1:2.12;49例发生在眼底荧光素造影期间和造影以后;与给药途径和给药速度有关;致过敏性休克的机制有多种;过敏试验不能完全预测过敏性反应。有6例死亡的病例报告。结论:荧光素用于眼底血管造影的不良反应比较多见,其中严重的不良反应过敏性休克多例,个别患者可因抢救不及时或不当而致死亡。加强用药监测是安全有效使用荧光素的重要保障。
Objective: To understand the characteristics and risk factors of anaphylactic shock induced by fluorescein and to provide a reference for the rational use of fluorescein in clinical practice. Methods: To retrieve the case reports of the medical database on the allergic shock caused by fluorescein, and to make statistics and analysis on the obtained literature. Results: A total of 46 cases of 46 cases of allergic shock caused by fluorescein were retrieved. Fluorescein-induced anaphylactic shock characteristics: more common in the elderly, male to female ratio of 1: 2.12; 49 cases occurred during fundus fluorescein contrast and after angiography; and route of administration and drug delivery rate; caused by anaphylactic shock There are many mechanisms; allergy tests do not fully predict anaphylaxis. There are 6 cases of death reported. Conclusion: The adverse reactions of fluorescein in fundus angiography are more common. Among them, severe adverse reactions have multiple cases of anaphylactic shock. Some patients may die of improper or improper salvage. Strengthening drug monitoring is an important guarantee for the safe and effective use of fluorescein.