比较分析了四种不同来源肝癌样品中神经节苷脂的高效硅胶薄板层析(HPTLC)图谱。结果表明,这四种不同来源的肝癌样品与正常肝的图谱比较,示有明显的变化,特别是在含双唾液酸的GD区域,所有肝癌样品都有一条含量较正常显著升高的带,而作为正常肝中神经节苷脂主要组分的GM_3在肝癌组织中则明显减少。 The high performance silica gel thin-plate chromatography (HPTLC) profiles of gangliosides in four different sources of liver cancer samples were compared and analyzed. The results showed that the four different sources of liver cancer samples compared with the normal liver showed significant changes, especially in the GD region containing di-sialic acid, all liver cancer samples have a significantly higher than normal levels of the band, However, GM3, which is a major component of gangliosides in the normal liver, was significantly reduced in hepatocellular carcinoma.