炎症小体是在细胞应激或感染时而活化组装的多蛋白复合物，是介导炎症反应的重要成分之一。炎症小体过度活化与多种人类疾病密切相关。目前发现，自噬是参与调控炎症小体活化的重要机制。因此，研究炎症小体以及自噬参与炎症小体调控的机制对于理解多种人类疾病的发病机理以及寻找治疗靶点提供重要依据。“,”Inflammasomes are molecular platforms activated upon cellular infection or stress, which are an important component of the inflammatory response.Excessive activation of inflammasome is closely related to a variety of human diseases.Recently, it has been found that autophagy is one of the important ways to regulate inflammasomes.Therefore, the study of inflammasomes and the mechanism by which autophagy participates in the regulation of inflammasomes provides an important basis for understanding the pathogenesis of various humans diseases and for finding therapeutic targets.