Rh系统抗体主要在输血及妊娠过程中产生。我国Rh阴性率虽然很低,仅有0.24％(D阴性),但因Rh系统的18种血型中,各型阴性率不同、所以输血产生Rh系统抗体的机遇较多。现将我院遇到的一例介绍如下: 病例介绍: 患者孙某、男性、35岁、因头晕乏力半年余、查血象发现白细胞明显增高、发烧38℃、脾大、WBC52.0× Rh system antibodies are mainly produced during blood transfusion and pregnancy. Rh-negative rate in our country is very low, only 0.24% (D-negative), but due to the Rh system of 18 kinds of blood type, the negative rate of each type is different, so there is more chance of producing Rh system antibody in blood transfusion. Cases are introduced: Sunmou, male, 35 years old, due to dizziness, fatigue more than six months, check the blood to find significantly higher white blood cells, fever 38 ℃, splenomegaly, WBC52.0 ×