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近年来随着心律失常电生理的研究进展,对抗心律失常的药物有了较迅速的发展和成就。据研究,心室肌纤维可分为两大类,心房心室及希氏束-蒲肯野氏属快反应纤维。窦房结及其周围的心肌纤维及房室结属慢反应纤维。在缺氧及钾离子浓度改变情况下快纤维可转化为具有慢反应特性。前者是由于细胞膜对钠离子的内流具有一个快速渠道,后者是细胞膜对
In recent years, with the progress of electrophysiological research of arrhythmia, anti-arrhythmic drugs have developed rapidly and achievements. According to the study, ventricular muscle fibers can be divided into two categories, atrial ventricular and His bundle - Purkinje fast-reacting fibers. Sinus node and its surrounding myocardial fibers and atrioventricular junction slow reaction fibers. Fibers can be converted to slow-reacting properties under hypoxic and potassium ion concentrations. The former is due to the cell membrane on sodium influx has a fast channel, which is the cell membrane pairs