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巯基蛋白酶抑制肽(cystatin or cysteine proteinase inhibitor,简称CPI),是一类小分子蛋白质,能够抑制巯基蛋白酶的活性。近年来国外许多学者对CPI开展了广泛的研究,孙诠曾在本刊介绍了鸡巯基蛋白酶抑制肽(鸡CPI)的研究现状。本文着重概述人巯基蛋白酶抑制肽(hCPI)的生物学功能及与临床医学的关系。
Cystatin or cysteine proteinase inhibitor (CPI) is a small class of protein that inhibits the activity of sulfhydryl protease. In recent years, many foreign scholars have carried out extensive research on CPI. Sun Quan introduced the research status of chicken thiol protease inhibitory peptide (chicken CPI) in this article. This article highlights the biological functions of human thiol protease inhibitor (hCPI) and its relationship with clinical medicine.