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肿瘤的生长是血管新生依赖性的。血管新生是由血管新生刺激因子和抑制因子之间平衡来调节。血管新生抑制剂可通过提高肿瘤细胞凋亡率来抑制肿瘤生长 ,提示血管新生与凋亡相关 ,凋亡受凋亡相关基因调控。凋亡相关基因与血管新生可能相关。
Tumor growth is angiogenesis-dependent. Angiogenesis is regulated by the balance between angiogenic stimulating and repressive factors. Angiogenesis inhibitors can inhibit tumor growth by increasing the rate of tumor cell apoptosis, suggesting that angiogenesis is related to apoptosis and apoptosis is regulated by apoptosis-related genes. Apoptosis-related genes may be related to angiogenesis.