The simultaneity and the regionality of the chemo-cycles are proved by cycle-to-cycle correlation integrated with conodont biostratigraphic correlation of the upper part of the Givetian (Devonian) between Liujing and Dale. The study indicates that these chemo-cycles with time spans of 0.10 Ma have an internal relation with paleoclimatic changes, and it might have an origin through Milankovitch eccentricity cyclicity. The simultaneity and the regionality of the chemo-cycles are proved by cycle-to-cycle correlation with conodont biostratigraphic correlation of the upper part of the Givetian (Devonian) between Liujing and Dale. The study indicates that these chemo-cycles with time spans of 0.10 Ma have an internal relation with paleoclimatic changes, and it might have an origin through Milankovitch eccentricity cyclicity.