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流行病学、分子学、遗传学等的研究表明,维生素D在前列腺癌的发展、浸润中起着重要作用。在实验模型和临床实验中1,25-二羟维生素D3[1,25-(OH)2D3]对前列腺上皮细胞癌具有抗增生,促分化、抗转移/浸润的作用。由于存在血钙增高的副作用,临床直接应用1,25-
Epidemiology, molecular studies, genetics and other studies have shown that vitamin D plays an important role in the development of prostate cancer and infiltration. 1,25-dihydroxyvitamin D3 [1,25- (OH) 2D3] has antiproliferative, differentiation-promoting and anti-metastatic / infiltration effects on prostate epithelial cell carcinoma in experimental models and clinical trials. Due to the presence of elevated serum calcium side effects, clinical direct application of 1,25-