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目的：探讨急性前壁Q波型心肌梗死（AMI）患者左心室重塑（LVRM）和左心室收缩功能（LVSF）。方法：将140例AMI患者随机分为静脉溶栓组和非溶栓组。采用Doppler超声心动图仪进行监测。结果：140例AMI患者LVRM总发生率为42．1％。溶栓组LVRM发生率明显低于非溶栓组（P＜0．05）。LVRM对LVSF产生明显影响。溶栓再通组LVRM发生率明显低于未再通组（P＜0．01），且LVSF明显得到改善（P＜0．01）。结论：AMI患者的LVRM发生率高，对LVSF有明显的影响。早期实施静脉溶栓治疗能减少LVRM发生，改善LVSF。
Objective: To investigate left ventricular remodeling (LVRM) and left ventricular systolic function (LVSF) in patients with acute anterior Q-wave myocardial infarction (AMI). Methods: 140 AMI patients were randomly divided into intravenous thrombolysis group and non-thrombolysis group. Doppler echocardiography was used for monitoring. Results: The overall incidence of LVRM in 140 AMI patients was 42.1%. The incidence of LVRM in thrombolytic group was significantly lower than that in non-thrombolytic group (P <0.05). LVRM has a significant effect on LVSF. The incidence of LVRM in thrombolytic group was significantly lower than that in non-recanalization group (P <0.01), and LVSF was significantly improved (P <0.01). Conclusion: The incidence of LVRM in patients with AMI is high, which has obvious effect on LVSF. Early intravenous thrombolytic therapy can reduce the incidence of LVRM, improve LVSF.