硝酸盐是用于处理严重心力衰竭的一种血管扩张药,可直接作用于平滑肌,使之松弛。其机理可能是硝酸盐与硝酸盐受体结合后激活了鸟苷酸环化酶,从而增加了环鸟苷酸(cGMP)的生成量,而这种 cGMP 是硝酸盐血管扩张作用的主要介质,这样,血 Nitrate is a vasodilator used to treat severe heart failure and acts directly on the smooth muscle to relax it. The mechanism may be the combination of nitrate and nitrate receptor activated guanylate cyclase, thereby increasing the production of cGMP, and this cGMP is the main mediator of the role of nitrate vasodilation, In this way, blood