论文部分内容阅读
目的了解停乳链球菌似马亚种临床分布特点及耐药性现状,为临床感染分析及指导合理用药提供依据。方法运用WHONET 5.6软件回顾性分析2013年1月-2016年12月杭州市中医院分离到的92株停乳链球菌似马亚种的临床致病特点及与耐药情况。结果 92株停乳链球菌似马亚种在痰液标本的分离率最高,为59.78%,其他依次为咽拭子、血液、创面脓液、宫颈拭子和尿液;临床分布以老年病科和儿科为主,分别占30.43%和15.22%。药敏结果显示92株菌的药敏表型较为一致,该菌对青霉素、阿莫西林、头孢噻肟、左旋氧氟沙星、氯霉素、万古霉素、复方新诺明均未出现耐药;对喹奴普丁-达副普汀、克林霉素耐药率较高且呈上升趋势;对红霉素耐药率最高,为100.00%。结论停乳链球菌似马亚种主要引起弱势人群的感染,临床应给予充分重视,并根据耐药性监测合理使用抗生素,减少广谱抗生素滥用情况。
Objective To understand the clinical distribution of Streptococcus dysgalactiae subsp. Equisimilis and the status of its drug resistance, so as to provide basis for clinical infection analysis and guidance of rational drug use. Methods The clinical pathogenicity and drug resistance of 92 Streptococcus faecalis strains isolated from Hangzhou Hospital of Traditional Chinese Medicine from January 2013 to December 2016 were retrospectively analyzed by WHONET 5.6 software. Results The isolation rates of 92 strains of Streptococcus dysgalactiae were the highest in sputum samples (59.78%), throat swabs, blood, wound pus, cervical swabs and urine in turn. The clinical distribution was geriatric And pediatrics, accounting for 30.43% and 15.22% respectively. The results of drug susceptibility showed that the susceptible phenotypes of 92 strains were consistent. The strains showed no resistance to penicillin, amoxicillin, cefotaxime, levofloxacin, chloramphenicol, vancomycin and cotrimoxazole The drug resistance to quinuptin-datimpudin and clindamycin showed a high and upward trend; the highest rate of erythromycin resistance was 100.00%. Conclusions Streptococcus dysgalactiae is the major cause of infection in the vulnerable population. Clinically, it should be given sufficient attention. Antibiotics should be used rationally according to drug resistance monitoring to reduce the abuse of broad-spectrum antibiotics.