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目的观察质量分数5%碳酸氢钠溶液洗胃治疗百草枯中毒的治疗效果。方法 142例百草枯中毒患者依据就诊时间分为2组,对照组49例应用常规清水洗胃,治疗组93例应用质量分数5%碳酸氢钠溶液洗胃并漱口,2组均给予谷胱甘肽、肾上腺皮质激素、环磷酰胺、血必净及血液灌流等综合治疗。比较2组治疗后口腔黏膜、肝脏、肾脏、肺损伤发生率,白细胞升高概率及病死率。结果对照组治疗后口腔溃疡、肝脏、肾脏、肺损伤发生率,白细胞升高概率及病死率均高于治疗组,差异有统计学意义(P<0.05)。结论百草枯中毒早期应用质量分数5%碳酸氢钠溶液洗胃效果优于清水洗胃。
Objective To observe the curative effect of paraquat poisoning by gastric lavage with 5% sodium bicarbonate solution. Methods 142 cases of paraquat poisoning patients were divided into two groups according to the time of treatment, the control group, 49 cases of conventional gastric lavage, 93 cases of treatment group with 5% sodium bicarbonate solution gastric lavage and mouthwash, Glycopeptide, adrenal cortex hormones, cyclophosphamide, Xuebijing and blood perfusion and other comprehensive treatment. Oral mucosa, liver, kidney, incidence of lung injury, leukocytosis and mortality were compared between the two groups. Results The oral ulcer, liver, kidney, lung injury, leukopenia and mortality in the control group were significantly higher than those in the treatment group (P <0.05). Conclusion Paraquat poisoning early application of 5% sodium bicarbonate solution gastric lavage is better than water lavage.