论文部分内容阅读
目的 通过在全省建立急性弛缓性麻痹 ( AFP)病例监测系统并开展脊髓灰质炎 (脊灰 )病毒学监测工作 ,证实湖南省实现无脊灰目标。 方法 收集全省 15岁以下 AFP病例及其接触者粪便标本 ,采用 WHO规定方法进行病毒分离与鉴定 ,脊灰阳性毒株送国家脊灰实验室进行型内鉴别。 结果 10年共检测 AFP病例粪便标本 14 0 4例 ( 2 760份 ) ,接触者粪便标本 2 16例 ,病毒分离阳性的 4 5 9例 ,其中脊灰 I型野病毒 7例 ,脊灰疫苗相关株病毒 92例 ,脊灰疫苗相关株病毒与肠道病毒混合 10例 ,非脊灰肠道病毒 3 5 0例 ,自 1993年 7月以后未再检出脊灰野病毒。 结论 监测结果表明我省实施的消灭脊灰策略效果显著 ,已成功地阻断了脊灰野病毒的传播 ,按期实现了区域无脊灰的目标
Objective To establish polio-free polio (AFP) case surveillance system in the province and monitor poliomyelitis (poliovirus) surveillance in Hunan Province, confirming the goal of polio-free in Hunan Province. Methods Stool specimens of AFP cases and their contacts under the age of 15 in the province were collected, virus isolation and identification were conducted according to WHO regulations, and positive strains of polio were sent to the National Polio Laboratory for in-vivo identification. Results A total of 14 074 cases (2 760) of stool specimens from AFP cases were detected in the past 10 years. There were 216 cases of stool samples from contact persons and 459 cases of positive virus isolates. Among them, 7 were poliovirus type I, 7 were poliovirus 92 cases of strains of virus, 10 strains of poliovirus-associated virus and enterovirus, 35 cases of non-polio enterovirus, and no poliovirus was detected since July 1993. Conclusion The monitoring results show that the strategy of eradication polio implemented in our province has achieved remarkable success and has successfully blocked the transmission of poliovirus and achieved the goal of no polio in a regular manner