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目的 观察中西医结合对视神经炎的治疗效果及其对图形视觉诱发电位的影响。方法 诊断为视神经炎的患者被分为中西医结合治疗组 (31例 )和西药组 (2 0例 )。两组患者分别接受中药联合西药治疗和单独应用西药治疗。在接受治疗的第 1 0d和 2 0d分别进行P -VEP检查并对其资料进行比较。结果 视神经炎患者在接受治疗前P -VEP检查的振幅下降 ,潜时延长。黑 /白 (0 388)和蓝 /青 (0 388)颜色P -VEP改变是大致相同的。红 /洋红颜色P -VEP的振幅明显变低 ,潜时明显延长。P -VEP异常的构成比比色觉检查异常的构成比高 (P <0 0 5 )。治疗后患者P -VEP的振幅升高 ,潜时缩短 ,其中潜时缩短发生的较晚 ,这一变化在黑 /白 (1 5 5 )和红 /洋红 (0 388)P -VEP检查中更为明显 (P <0 0 5 )。治疗 2 0d后两组振幅变化比较差异无显著性 (P>0 0 5 )。结论 中西医结合是治疗视神经炎的有效方法之一。颜色P -VEP在视神经炎的诊断和疗效判断中具有重要意义
Objective To observe the therapeutic effect of integrated traditional Chinese and western medicine on optic neuritis and its effect on visual evoked potentials. Methods Patients diagnosed as optic neuritis were divided into two groups (31 cases) and western medicine group (20 cases). Two groups of patients received traditional Chinese medicine combined with western medicine and Western medicine alone. P-VEP was examined on the 1 0d and 2 0d after treatment and their data were compared. Results The amplitude of P-VEP in patients with optic neuritis before treatment was declining, prolonged. The black / white (0 388) and blue / blue (0 388) color P -VEP changes are about the same. The red / magenta color P -VEP amplitude was significantly lower, the potential was significantly extended. The composition of P-VEP abnormality was higher than that of abnormal colorimetry (P <0 05). After treatment, the amplitude of P-VEP was increased and the latency was shortened, and the shortening of latent shortening occurred later. The change was more in black / white (15 5) and red / magenta (0 388) P -VEP As obvious (P <0 05). There was no significant difference in amplitude between two groups after 20 days of treatment (P> 0.05). Conclusion Integrative Medicine is one of the effective ways to treat optic neuritis. Color P -VEP in the diagnosis and treatment of optic neuritis have important significance