论文部分内容阅读
目的:探讨乳腺颗粒细胞瘤(GCT)的临床病理特征、诊断、鉴别诊断和预后。方法:复习一例乳腺GCT的临床资料,进行组织细胞形态和免疫组织化学观察。结果:此例GCT临床症状及体征无明显特殊性,但是镜下结构及生长方式特殊,细胞核很小,无异型性,胞质呈嗜酸性、细颗粒状,红染,呈假浸润状生长。免疫组化结果:S-100阳性,CK阴性,ER阴性,PR阴性。结论:乳腺颗粒细胞瘤很少见,临床、细胞学及冰冻检查很容易误诊为恶性,因此,要提高对此病的认识,尤其是在病理冰冻检查中,以减少不必要的过度治疗。
Objective: To investigate the clinicopathological features, diagnosis, differential diagnosis and prognosis of granulosa cell tumor of the breast (GCT). Methods: To review the clinical data of a case of breast GCT and observe the morphology and immunohistochemistry of the cells. Results: The clinical symptoms and signs of GCT showed no particularity in this case. However, the microscopic structure and growth pattern of GCT were very special. The nucleus was small and non-atypical. The cytoplasm was eosinophilic, finely grained, reddish and pseudohyphagic. Immunohistochemical results: S-100 positive, CK negative, ER negative, PR negative. CONCLUSIONS: Breast granulocytoma is rare, and clinical, cytologic, and cryoablative tests are easily misdiagnosed as malignant. Therefore, awareness of the disease should be raised, especially in pathological frozen exams, to reduce unnecessary over-treatment.