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肝细胞腺瘤属良性肿瘤,发生率很低。Edmondson在50000多例尸检中(1918~1954年),仅发现2例肝细胞腺瘤。1973年Baum首先报道口服避孕药与肝细胞腺瘤有关。他指出,避孕药及其同类药物,可引起肝细胞腺瘤。还有人报道肝细胞腺瘤发生于Ⅰ型糖原储存病。此外还有巨大肝细胞腺瘤导致肾性高血压的报道。 1 病理特点肝细胞腺瘤多发生于无硬变的肝右叶内(左叶少见)。为单发性圆形肿瘤,境界清楚,包膜完整,也可无包膜,表面血管丰富,直径从1~20cm不等。切面呈棕黄色或黄色。有时可见
Hepatic cell adenoma is a benign tumor with a low incidence. Edmondson found only 2 cases of hepatocellular adenomas in more than 50,000 autopsy cases (1918 to 1954). In 1973, Baum first reported that oral contraceptives were associated with hepatocellular adenomas. He pointed out that contraceptives and their generic drugs can cause hepatocellular adenomas. It has also been reported that hepatocellular adenomas occur in type I glycogen storage disorders. There are also reports of giant hepatocyte adenomas leading to renal hypertension. 1 pathological features of hepatocellular adenomas occur in the right hepatic lobe without hardening (common in the left lobe). For a single round of tumor, the realm is clear, the capsule is complete, and there is no capsule. The surface blood vessels are abundant, ranging in diameter from 1 to 20cm. Sections are brown or yellow. Sometimes visible