为了判断溶菌酶对输血后肝炎的预防效果,作者进行了一项随机、设对照的研究。研究对象选自1970年6月至1975年5月在一家医院里作矫形外科手术的病人。作者将260例输血超过400ml并可供随访的患者随机分为两组:治疗组123例,在手术期间或手术后立即使用溶菌酶,剂量为60～180mg/日,分三次口服,用药时间为4～24周,平均13.7周;对照组137例。在手术前后对患者作肝功能检查。输血后肝炎的诊断标准为: In order to determine the prophylactic effect of lysozyme on post-transfusion hepatitis, the authors conducted a randomized, controlled study. The subjects were selected from patients who underwent orthopedic surgery in a hospital from June 1970 to May 1975. The authors randomized 260 patients who were transfused to more than 400ml and were followed up. Patients in the treatment group were randomly divided into two groups: 123 in the treatment group. Lysozyme was used during or immediately after surgery at a dose of 60-180mg / day orally in three doses 4 to 24 weeks, an average of 13.7 weeks; control group of 137 cases. Liver function tests were performed on patients before and after surgery. Post-transfusion hepatitis diagnostic criteria are: