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选取2013年10月~2014年9月两院收治的肠易激综合征病例75例,随机分为试验组38例和对照组37例。试验组采用西酞普兰加消化科药物治疗,对照组单用消化科药物治疗,观察对比两组临床疗效及HAMA评分、HAMD评分。结果试验组总有效率94.74%,对照组总有效率70.27%,组间差异有统计学意义(P<0.05)。治疗后,试验组HAMA总分、HAMD总分均明显低于对照组,组间差异有统计学意义(P<0.05)。采用西酞普兰治疗肠易激综合征,具有改善患者焦虑抑郁情绪与消化系统病状的作用,值得推广应用。
A total of 75 cases of irritable bowel syndrome (IBS) treated in both hospitals from October 2013 to September 2014 were randomly divided into experimental group (38 cases) and control group (37 cases). The experimental group was treated with citalopram plus digestive medicine, while the control group was treated with digestive medicine alone. The clinical efficacy, HAMA score and HAMD score were compared between the two groups. Results The total effective rate was 94.74% in the experimental group and 70.27% in the control group. The difference between the two groups was statistically significant (P <0.05). After treatment, the scores of HAMA and HAMD in the experimental group were significantly lower than those in the control group, with significant difference between the two groups (P <0.05). The use of citalopram in the treatment of irritable bowel syndrome has the effect of improving anxiety, depression and digestive system symptoms in patients and is worth promoting.