目的 :对广西急性毒鼠强中毒病例进行总结 ,探讨其应急救治方法 (毒鼠强解毒鸡尾酒疗法 ) ,更好地指导毒鼠强中毒的抢救工作。方法 :对广西职业病防治研究所住院急救的 79例急性毒鼠强中毒者 ,结合作者对发生于全自治区 30起共 76 7例群体性急性毒鼠强中毒者的现场抢救指导或急性毒鼠强会诊的应用效果进行整理分析。其应急救治方法主要为 :1排毒 :尽早催吐、反复彻底洗胃 ;及早使用大剂量利尿剂或血液净化疗法清除胃内或血中的毒鼠强 ;2抗惊厥和拮抗毒鼠强 :使用苯巴比妥钠 ,按抗惊厥量 ,每间隔 4 h静脉注射 1次 ,同时配合大剂量静脉注射安定和纳络酮 ;3非特异解毒综合疗法 :以使用自由基清除剂还原型谷胱甘肽和 1,6 -二磷酸果糖为主 ;配用大剂量激素和超大剂量维生素 B6 ;危重症中毒患者加用乌司他丁和脑活素 ;慎用二巯基丙磺酸钠 ;4积极防治脑水肿 ,早期使用脱水剂 ,2 0 %甘露醇并间隔使用 30 %～ 5 0 %葡萄糖溶液 ;酌情配用高压氧治疗和量子血治疗 ;5按内科急重症常规进行对症治疗和支持疗法 ,酌情配合使用细胞活化药物及抗生物氧化剂。结果 :经采用以上五方面的积极应急救治后 ,84 6例中毒者无一例死亡。结论 :通过采用以上五方面的应急救治方法 (毒鼠强解毒鸡尾酒疗法 ) ,能有效的降低毒鼠强中毒的 Objective: To summarize the cases of acute tetramine poisoning in Guangxi and discuss its emergency treatment method (tetramine poisoning detoxification cocktail therapy) to better guide the rescue of tetramine poisoning. Methods: A total of 79 cases of acute tetramine poisoning hospitalized by Guangxi Institute of Occupational Disease Prevention and Treatment were enrolled in the study. A total of 767 cases of acute tetramine poisoning occurred in 30 districts of the Autonomous Region, Appraisal of the application of the effect of finishing analysis. The emergency treatment methods are as follows: 1 detoxification: as soon as vomiting, repeated gastric lavage; early use of high-dose diuretic or blood purification therapy to remove the stomach or blood of tetramine; 2 anticonvulsant and antagonism tetramine strong: the use of benzene Barbital sodium, according to the amount of anticonvulsant, every 4 h intravenous injection 1, at the same time with high-dose intravenous stability and naloxone; 3 non-specific detoxification therapy: the use of free radical scavengers reduced glutathione And 1,6-diphosphate-based; with high-dose hormone and large doses of vitamin B6; critically ill patients with ulinastatin and cerebrolysin; caution with sodium dimercaptopropane sulfonate; 4 active prevention and control of brain Edema, the early use of dehydrating agent, 20% mannitol and 30% ~ 50% glucose solution interval; with hyperbaric oxygen therapy and quantum blood treatment, as appropriate; 5 according to the urgent need for medical treatment of symptomatic and supportive therapy, as appropriate Use cell-activating drugs and anti-oxidants. Results: After adopting the positive emergency treatment in the above five aspects, none of the 846 poisoned persons died. Conclusion: By using the above five aspects of emergency treatment (tetramine poisoning cocktail therapy), can effectively reduce the toxic tetramine poisoning