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目的通过研究宁夏地区生育障碍男性染色体异常的发生率,探讨染色体检查的必要性。方法对2015年1月至2016年10月期间有异常生育史的657例男性患者抽取外周血常规培养,G显带并进行核型分析。结果 657例男性患者中,染色体异常131例,异常率为19.94%。结论染色体异常是导致男性异常生育的重要因素之一,在男性生育障碍患者的临床诊断和治疗时,进行染色体检查十分必要。
Objective To investigate the incidence of male chromosomal abnormalities in reproductive disorders in Ningxia and to explore the necessity of chromosome examination. Methods A total of 657 male patients with abnormal birth history from January 2015 to October 2016 were enrolled in this study. Peripheral blood routine culture, G-banding and karyotyping were performed. Results Among the 657 male patients, 131 cases were chromosomal abnormalities with an abnormality rate of 19.94%. Conclusions Chromosomal abnormalities are one of the most important factors that lead to abnormal male fertility. It is necessary to carry out chromosomal examination in the clinical diagnosis and treatment of male fertility disorders.