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目的探讨普拉克索对不宁腿综合症(RLS)患者治疗的临床疗效。方法将30例患者随机分为对照组和治疗组,两组为继发性RLS患者均治疗原发病,同时给予非药物治疗和氯硝西泮,治疗组在上述治疗的基础上加用普拉克索,以治疗前后匹兹堡睡眠质量指数(PSQI)和RLS严重程度量表(IRLSSG)评分进行评估疗效。结果两组治疗后PSQI和IRLSSG评分明显降低,组内和组间比较差异均有统计学意义(P<0.05)。结论普拉克索治疗RLS有效,值得临床应用。
Objective To investigate the clinical effect of pramipexole on restless legs syndrome (RLS) patients. Methods Thirty patients were randomly divided into control group and treatment group. The two groups were secondary to RLS, both were treated with non-drug therapy and clonazepam. The treatment group was treated with P Laksone was evaluated for Pittsburgh Sleep Quality Index (PSQI) and RLS Severity Scale (IRLSSG) scores before and after treatment. Results The scores of PSQI and IRLSSG were significantly decreased in both groups after treatment, with significant difference between the two groups (P <0.05). Conclusions Pramipexole is effective in treating RLS and is worthy of clinical application.