本文采用Metcalf改良的体外单层琼脂培养技术,对40例胎龄3个月到足月非药物引产正常胎儿的骨髓、肝、脾和周围血的体外集落形成单位(CFU-C)进行了研究。本实验表明,1.骨髓在胎龄3个月时已有CFU-C存在,4个月时CFU-C产率达到很高水平,并一直保持到出生前;2.胎肝在4～6月为CFU-C产率的高峰期,7个月迅速下降,到出生前一直处于较低水平;3.胎脾CFU-C水平较低;4.胎儿周围血中CFU-C水平较高,但低于肝和骨髓。 In this study, Metcalf modified in vitro monolayer agar culture in 40 cases of gestational age 3 months to full-term non-drug-induced fetal normal fetal bone marrow, liver, spleen and peripheral blood in vitro colony-forming units (CFU-C) were studied . This experiment shows that 1. CFU-C exists in the bone marrow at 3 months gestational age, and the CFU-C yield reaches a very high level at 4 months and remains until birth. 2. The fetal liver is in the range of 4 to 6 Month was the peak of CFU-C production rate, which dropped rapidly in 7 months and remained low until birth; 3. The level of CFU-C in fetal spleen was low; 4. The level of CFU-C in fetal peripheral blood was high, But lower than the liver and bone marrow.