T_1G_3膀胱癌二次电切治疗体会

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[目的]探讨T1G3膀胱癌行第二次经尿道电切术(ReTUR)的必要性。[方法]回顾性分析37例经尿道膀胱肿瘤电切术(TURBt)明确为T1G3膀胱癌患者资料。单发乳头状肿瘤15例,多发乳头状肿瘤17例,广基型肿瘤5例。4~6周后再次电切,术后常规丝裂霉素膀胱内灌注化疗。[结果]所有肿瘤切除标本均含有肌层组织。二次电切中13例(13/37,35.1%)发现有残余肿瘤,2例(2/37,5.4%)发现肿瘤为T2期,更改治疗方案。1例(1/15,6.7%)单发乳头状肿瘤,8例(8/17,47.1%)多发乳头状肿瘤,4例(4/5,80.0%)广基型肿瘤发现癌细胞残留。[结论]不同的T1G3患者在二次电切中结果不尽相同。对多发乳头状和广基型的肿瘤应常规行二次电切,而对单发乳头状肿瘤可酌情考虑。 [Objective] To investigate the necessity of second transurethral resection (ReTUR) of T1G3 bladder cancer. [Method] Thirty-seven cases of TURBT were retrospectively analyzed for the data of T1G3 bladder cancer. Single papillary tumor in 15 cases, multiple papillary tumors in 17 cases, 5 cases of wide-based tumors. 4 to 6 weeks after the resection, postoperative chemotherapy mitomycin bladder intravesical instillation. [Results] All tumor resected specimens contained muscular tissue. 13 cases (13/37, 35.1%) in secondary resection found residual tumor, 2 cases (2 / 37,5.4%) found that the tumor was T2, and changed the treatment plan. One (1 / 15,6.7%) single papillary tumor, 8 (8 / 17,47.1%) multiple papillary tumors, and 4 (4 / 5,80.0%) wide-based tumors found residual cancer cells. [Conclusion] Different T1G3 patients have different results in secondary electrosurgery. Multiple papillary and broad-based tumors should be routine secondary resection, and single papillary tumors may be discretionary.
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