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继发性骨髓增生异常综合征(MDS)近年来国外文献已有记载,而国内文献报道很少,本文结合文献报道5例继发性MDS。1 临床资料1.1 一般资料:我院自1984年1月~1990年12月收住47例MDS病人,其中5例属继发性MDS(发生率10.6%),男性1例,女性4例,年龄37~55岁,平均年龄48.6岁。1.2 MDS类型:RA 1例,RAEB 3例,RAEB-t 1例。1.3 原发病和可能病因:2例乳腺癌病人长期应用塞替派(1例RA,1例RAEB),1例银屑病病人长期应用乙双鸣啉(RAEB),1例精神分裂症长期应用多虑平(RAEB),1例长期接触放射线(RAEB-t)。
Secondary myelodysplastic syndrome (MDS) in recent years, foreign literature has been documented, and few domestic literature reported in this paper combined with 5 cases reported in the literature of secondary MDS. 1 Clinical data 1.1 General Information: Our hospital from January 1984 to December 1990, admitted to 47 cases of MDS patients, of which 5 cases are secondary to MDS (incidence 10.6%), 1 males and 4 females, age 37 ~ 55 years old, average age 48.6 years old. 1.2 MDS type: RA 1 case, RAEB 3 cases, RAEB-t 1 case. 1.3 primary disease and possible causes: two cases of breast cancer patients long-term use of thiotepa (1 case of RA, 1 case of RAEB), 1 case of psoriasis patients long-term use of bishoprin (RAEB), 1 case of schizophrenia long-term Application of doxepin (RAEB), 1 case of long-term exposure to radiation (RAEB-t).