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CD147在人体各种肿瘤组织中广泛表达。大量研究表明，其能诱导基质金属蛋白酶的产生，并且在肿瘤细胞的生长增殖和转移浸润中具有非常重要的作用。通过大量的对 CD147影响肿瘤细胞的生长增殖和转移浸润等作用机制的研究，学者们试图在肿瘤的诊断、辅助治疗及判定肿瘤治疗预后等方面为临床肿瘤的治疗提供新的方法，并且已取得了一定的成果。 CD147与肿瘤的关系近年来一直是研究的热点，该文就CD147与恶性肿瘤治疗关系的研究进展予以综述。“,”The expression of CD147 raises significantly in many malignant tumors .Many studies have shown that CD147 can facilitate the invasion of malignant tumors via stimulating matrix metalloprotease (MMP) production and play an important role in growth,invasion,metastasia of tumors.Through a lot of re-searchof the mechanism of CD147 effect of tumor cell growth and proliferation and invasion and metastasis ,we tried to find some new methods in tumor diagnosis ,treatment and prognosis judgment of these tumor progno-sis,and has achieved certain results.Therefore,the relationship between CD147 and tumor in recent years has been the focus of research.