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资料来源于本院药库1996～1998年药品临床使用出库统计表。参照《中国药典》95版《新编药物学》第14版所提供的药物常用日剂量,结合药物出库数量,计算药物的消耗治疗日(即消耗治疗日=药物出库数量/药物常用剂量)。以年份和构成比作变量计算回归方程,通过回归系数b的大小比较考查各类药品构成比随年份的变化趋势(计算方法和公式来源于《药师手册》)。结果显示,常用的30种抗感染药物消耗治疗日总量逐年上升,1997年比1996年增加9.53％,1998年比1997年增加3.60％。喹诺酮类、大环内酯类、头孢菌素类、磺胺类、氨基糖甙类、抗病毒类、抗真菌
Data from the hospital pharmacies 1996 to 1998 clinical use of drugs out of the library statistics. With reference to the commonly used daily dose of drugs provided by the 95th edition of the “Pharmacopoeia of the People’s Republic of China” and the 14th edition of “New Pharmacology” of the Chinese Pharmacopoeia, the number of drug excretion days (that is, the expelling treatment day = the number of excreted drugs / the common dose of drugs) ). The year and composition ratio are used as variables to calculate the regression equation, and the comparisons of composition ratios of all kinds of drugs with years are made by the comparison of the size of the regression coefficient b (the calculation method and formula are from the Manual of the Pharmacists). The results showed that the total daily consumption of 30 commonly used anti-infective drugs increased year by year, increasing by 9.33% from 1997 to 1996 and 3.60% from 1998 to 1997. Quinolones, macrolides, cephalosporins, sulfonamides, aminoglycosides, antivirals, antifungal