根据氧同位素构成的不同可以对铀矿石进行地理定位,本工作采用TIMS对氧化铀中的氧同位素比进行了测量。研究了不同的蒸发电离温度程序、不同载体试剂、不同材料及结构的样品带、测量方式、微粒大小等因素对氧化铀中氧同位素比测量结果和精度的影响,重点研究了不同试剂作为 Uranium ore can be geolocated according to the composition of oxygen isotope. In this work, the oxygen isotope ratio of uranium oxide was measured by TIMS. The effects of different evaporation temperature programs, samples with different carriers, samples with different materials and structures, measurement methods, particle size and other factors on the measurement results and accuracy of oxygen isotope ratio in uranium oxide were studied. The effects of different reagents