论文部分内容阅读
目的分析血清前列腺特异性抗原(PSA)及游离前列腺特异性抗原(fPSA)与良性前列腺增生(BPH)临床的相关性。方法应用化学发光微粒子免疫分析法(CMIA)对BPH患者血清PSA、fPSA进行检测。结果入选的40例患者病理均为BPH。PSA>4ng/ml者,术后随访1～3个月,平均2.5个月,PSA值均降至0.02ng/ml以下,可除外前列腺癌(PCa)病例。PSA<4ng/ml者16例(40%),4～10ng/ml者14例(35%),>10ng/ml者10例(25%);fPSA>0.934ng/ml者22例(55%)。血清PSA、fPSA水平与前列腺总体积(PV)、前列腺移行区体积(TZV)、年龄及国际前列腺症状评分(IPSS)呈正相关。结论本组血清fPSA与PV、TZV、年龄、IPSS评分有更强相关性。BPH患者血清PSA、fPSA水平升高的相关因素与前列腺总体积及移行区增大、高龄及高IPSS评分有关。
Objective To analyze the correlation between serum PSA and free prostate specific antigen (fPSA) and benign prostatic hyperplasia (BPH). Methods Chemiluminescence microparticle immunoassay (CMIA) was used to detect serum PSA and fPSA in patients with BPH. Results The selected 40 patients were pathologically BPH. PSA> 4ng / ml were followed up for 1 to 3 months, an average of 2.5 months, PSA values were reduced to 0.02ng / ml or less, except for cases of prostate cancer (PCa). 16 cases (40%) with PSA <4ng / ml, 14 cases (35%) with 4-10ng / ml and 10 cases (> 25%) with> 10ng / ). Serum PSA, fPSA levels were positively correlated with total prostate volume (PV), prostate transitional volume (TZV), age and International Prostate Symptom Score (IPSS). Conclusion This group of serum fPSA and PV, TZV, age, IPSS score has a stronger correlation. BPH patients with elevated serum PSA, fPSA related factors and the total prostate volume and transition area increased age and high IPSS score.