本文对8例新生儿肾小管性酸中毒的临床资料进行分析,发病年龄均在出生20天之内。男女之比为7:1。主要症状为反复发热、频繁呕吐、哭吵、呼吸急促、不明原因及难以纠正的脱水酸中毒,血气分析提示有代谢性酸中毒,多系高氯性酸中毒;尿pH在6.0～8.0。确诊后给大量碱剂,常用者为10％枸橼酸钠钾治疗,纠正脱水酸中毒,使临床症状消失。同时,本文对肾小管性酸中毒的分型问题加以讨论。 In this paper, 8 cases of neonatal renal tubular acidosis clinical data analysis, the age of onset are within 20 days of birth. The ratio of men to women is 7: 1. The main symptoms of recurrent fever, frequent vomiting, crying noisy, shortness of breath, unexplained and difficult to correct dehydration acidosis, blood gas analysis prompted metabolic acidosis, multi-line high chloride acidosis; urine pH 6.0 ~ 8.0. After the diagnosis to a large number of alkali agents, commonly used 10% sodium citrate potassium treatment to correct dehydration acidosis, the clinical symptoms disappear. At the same time, this article discusses the classification of renal tubular acidosis.