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目的探讨与克拉玛依人群糖耐量低减 (IGT)和 2型糖尿病发病有关的危险因素。方法对克拉玛依市参加过1994～ 1995年全国糖尿病普查的 2 0 8例曾进行饮食问卷者进行饮食和临床分析 (其中正常糖耐量 87例 ,IGT5 4例 ,新诊断糖尿病 6 7例。)结果 IGT组和新诊断糖尿病组饮食总热量 ,蛋白质 ,脂肪 ,饱和脂肪酸、单不饱和脂肪酸、多不饱和脂肪酸摄入 ;以及体质指数 (BMI)、血空腹胰岛素和甘油三酯水平均明显高于正常组 (P分别 <0 .0 5和 <0 .0 1)。 L ogistic逐步回归分析显示 BMI和脂肪摄入与 IGT、糖尿病发病显著正相关 (P<0 .0 1)。结论肥胖、高脂肪饮食是克拉玛依人群IGT和 2型糖尿病发病的危险因素。合理的膳食和运动、很好的控制体重对预防 IGT和 2型糖尿病发病十分重要
Objective To investigate the risk factors associated with the impaired glucose tolerance (IGT) and type 2 diabetes in Karamay. Methods Diet and clinical analysis were performed on 280 subjects who had participated in the National Diabetes Surveillance from 1996 to 1995 in Karamay. Among them, 87 were normal glucose tolerance, 4 were IGT5 and 67 were newly diagnosed with diabetes.) Results IGT Dietary calorie, protein, fat, saturated fatty acids, monounsaturated fatty acids and polyunsaturated fatty acids intake in group and newly diagnosed diabetes mellitus group; and body mass index (BMI), blood fasting insulin and triglyceride levels were significantly higher than those in normal group (P <0. 05 and <0. 01 respectively). L ogistic stepwise regression analysis showed that there was a significant positive correlation between BMI and fat intake and IGT and diabetes incidence (P <0.01). Conclusion Obesity and high-fat diet are the risk factors of IGT and type 2 diabetes in Karamay. Reasonable diet and exercise, good weight control is very important to prevent the onset of IGT and type 2 diabetes