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目的对2003年1月-2011年1月衡水市妇幼保健院新生儿甲状腺功能低下症筛查的情况进行分析总结,资料来源于这期间我院筛查的392338例新生儿。方法采用Wellscan-MK3型酶标仪,测定采用ELISA方法,检测血促甲状腺激素。结果 (1)2003年1月～2011年1月本中心共计筛查的新生儿392338例,确诊先天性甲低268例,发病率约是1∶1465。这一结果明显高于全国的平均水平。(2)筛查的覆盖率也由2003年的51.1%上升至2011年的98%。(3)经过正规治疗,267例患儿平均智商达85分以上。(4)开展这项工作可以尽早的发现疾病,及早给予治疗,避免造成儿童生长发育障碍、智能落后、神经系统功能损害等严重后果,对提高人口素质,推动国民经济发展有着重要的意义。
Objective To analyze and summarize the screening of neonatal hypothyroidism in Hengshui MCH from January 2003 to January 2011. The data are from 392 338 newborns in our hospital during this period. Methods Wellscan-MK3 microplate reader was used to detect serum thyrotropin by ELISA. Results (1) From January 2003 to January 2011, a total of 392,338 newborns were screened in our center. 268 cases of congenital hypothyroidism were diagnosed. The incidence rate was about 1:1465. This result is clearly above the national average. (2) The screening coverage also increased from 51.1% in 2003 to 98% in 2011. (3) After formal treatment, 267 children with an average of more than 85 points of intelligence. (4) To carry out this work can detect the disease as soon as possible, treat it as soon as possible, and avoid the serious consequences of children’s growth and development disorders, intellectual backwardness and nervous system dysfunction, which are of great significance to improving population quality and promoting national economic development.