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胃泌素(Gastrin)是一种重要的胃肠道激素,由胃、肠的G细胞所分泌。正常G细胞分布于胃窦、十二指畅和近端空畅。舌、食道、胃底、远端空肠和回肠也可分泌少量胃泌素,胰岛D细胞亦能分泌胃泌素。胃泌素是体内具有最强作用的胃粘膜“营养激素”,它可促使胃粘膜血流增加,粘膜上皮细胞中DNA和RNA合成加速,细胞代谢增快,以及使泌酸、泌酶功能增强。此外,它还可促进胃肠道蠕动,松弛幽门、胆道及迥盲部括约肌,但可使食道下
Gastrin is an important gastrointestinal hormone that is secreted by G cells in the stomach and intestine. Normal G cells are distributed in the antrum of the stomach, the twelve fingers are smooth, and the proximal one is free. The tongue, esophagus, stomach, distal jejunum and ileum also secrete a small amount of gastrin, and islet D cells can also secrete gastrin. Gastrin is the most potent gastric mucosal “nutritional hormone” in the body. It can increase the blood flow of gastric mucosa, accelerate the synthesis of DNA and RNA in mucosal epithelial cells, increase the metabolism of cells, and increase the secretion of oxyntic acid and secretion enzymes. . In addition, it can promote gastrointestinal motility, relaxation of the pyloric, biliary and orbital septum, but can make the esophagus