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目的:将非药物性干预措施与传统药物方法治疗极低出生体重儿喂养不耐受的临床疗效进行观察比较。方法:选取哈尔滨医科大学附属第二医院2011年1月至2013年4月出生的喂养不耐受极低出生体重儿110例。按入院顺序随机分为药物治疗组(MED)55例、非药物治疗组(NON-MED)55例。药物治疗组采用红霉素;非药物治疗组采用腹部按摩法与非营养性吸吮。结果:两组患儿经治疗后,MED组腹胀消失天数(4.4±0.5)、呕吐天数(2.2±0.5)、每日呕吐次数(3.5±0.8)、胃潴留量占每日喂养量(18.3±0.8)、达全肠道喂养天数(8.2±0.7);NON-MED组腹胀消失天数(3.7±0.1)、呕吐天数(1.9±0.6)、每日呕吐次数(2.8±0.1)、胃潴留量占每日喂养量(12.6±0.4)、达全肠道喂养天数(6.1±0.3)。各项治疗指标的对比中,差异均有统计学意义(P<0.05)。MED组治疗有效率76.4%;NON-MED组治疗有效率83.6%。结论:非药物性干预措施可有效改善极低出生体重儿喂养不耐受。
OBJECTIVE: To compare the clinical efficacy of non-drug-based interventions with those of traditional medicines in the treatment of very low birth weight infants intolerant. Methods: A total of 110 infants with very low birth weight were enrolled in the Second Affiliated Hospital of Harbin Medical University from January 2011 to April 2013. According to the order of admission, 55 cases were randomly divided into drug treatment group (MED) and non-drug treatment group (NON-MED). Drug treatment group with erythromycin; non-drug treatment group using abdominal massage and non-nutritive sucking. Results: After treatment, the days of abdominal distension and disappearance (4.4 ± 0.5), days of vomiting (2.2 ± 0.5), vomiting (3.5 ± 0.8), and gastric retention (18.3 ± 0.8), reaching the total intestine feeding days (8.2 ± 0.7); NON-MED group (3.7 ± 0.1 days), days of vomiting (1.9 ± 0.6), daily vomiting (2.8 ± 0.1), gastric retention Daily feeding volume (12.6 ± 0.4), reaching full intestine feeding days (6.1 ± 0.3). The comparison of various treatment indicators, the differences were statistically significant (P <0.05). MED treatment efficiency 76.4%; NON-MED group treatment efficiency 83.6%. Conclusion: Nonpharmacologic interventions can effectively prevent intolerance in very low birth weight infants.