目的：探讨高脂血症患者血液流变学的变化。方法：对３９例单纯高脂血症患者和６０例健康人进行７项血液流变学指标的测定，再作对比。结果：高脂血症患者低切变率全血比粘度、血沉、红细胞电泳时间、聚集指数和血浆比粘度均显著高于健康对照组（Ｐ＜０．０５～０．００１）。结论：高脂血症患者血液流变学有显著的异常，应注意其多项指标的检测。 Objective: To investigate the changes of hemorrheology in patients with hyperlipidemia. Methods: Thirty-nine patients with hyperlipidemia and 60 healthy subjects were enrolled in this study. Seven hemorrheological parameters were measured and compared. Results: Low shear rate whole blood specific viscosity, erythrocyte sedimentation rate, erythrocyte electrophoresis time, aggregation index and plasma viscosity were significantly higher in patients with hyperlipidemia than those in healthy controls (P <0.05-0.001). Conclusion: There are significant abnormalities in hemorrheology in patients with hyperlipidemia. Attention should be paid to the detection of multiple indicators.