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背景:在幼儿接种流感嗜血杆菌-脑膜炎C/Y结合疫苗(HibMenCY-TT)疫苗的第二年进行单剂四价脑膜炎球菌结合疫苗(Men ACWY-TT)或第四剂Hib Men CY-TT的安全性和免疫原性的评价。方法:健康婴儿被随机(5∶1)分组,在2、4和6个月龄接种Hib Men CY-TT和白喉-破伤风-无细胞百日咳-乙肝-灭活脊髓灰质炎病毒(DTa PHBV-IPV)疫苗;或Hib-TT和DTaP-HBV-IPV疫苗(对照组)。
Background: The monovalent quadrivalent meningococcal conjugate vaccine (Men ACWY-TT) or the fourth dose of Hib Men CY was administered in the second year of young children vaccinated with the Hib vaccine (HibMenCY-TT) Evaluation of the safety and immunogenicity of -TT. METHODS: Healthy infants were randomized (5: 1) into groups, with Hib Men CY-TT and diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus (DTa PHBV- IPV) vaccine; or Hib-TT and DTaP-HBV-IPV vaccines (control group).